Prostaglandin E2 production by glomeruli and collecting tubules isolated from rat kidney.

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Prostaglandin E2 production by glomeruli and collecting tubules isolated from rat kidney.

The effects of vasopressin, angiotensin II, and calcium ionophore A23187 were examined and compared on endogenous prostaglandin E2 (PGE2) production, in the absence of exogenous arachidonate, by glomeruli and cortical and medullary collecting tubules freshly prepared from rat kidney. Angiotensin II stimulated PGE2 production in the glomeruli but not in the collecting tubules. Vasopressin at con...

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Abnormalities in glomerular function have been observed frequently in the early stages of both clinical and experimental diabetes mellitus. Because prostaglandins (PGs) are present in the glomerulus and have profound effects on glomerular hemodynamics, and because abnormalities of PG metabolism have been noted in other tissues from diabetics, we studied PG biosynthesis in glomeruli obtained fro...

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To ascertain whether prostaglandins (PG) may play a role in the secretion of glucagon and in an attempt to elucidate the conflicting observations on the effects of PG on insulin release, the isolated intact rat pancreas was perfused with solutions containing 1.1 x 10(-9) to 1.8 x 10(-5)m PGE2. In the presence of 5.6 mM glucose significant increments in portal venous effluent levels of glucagon ...

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by isolated rat renal tubules

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ژورنال

عنوان ژورنال: The Japanese Journal of Physiology

سال: 1987

ISSN: 1881-1396,0021-521X

DOI: 10.2170/jjphysiol.37.631